Tuesday 12 September 2017

image Q. 80 - Bisphosphonate blues

Q.  Which of these is advocated after taking bisphosphonates for management of osteoporosis?


a. Drug to be taken with meal
b. Immediate supine position to counter postural hypotension
c. Upright posture after medication
d. Continuous blood pressure monitoring
























































































































































































Answer -
c
The patient is advised to take these medicines empty stomach with a glass of water and be upright for half to an hour and not to lie supine to avoid esophageal irritation or gastric ulcers.
Intravenous bisphosphonates are used in cases with gastrointestinal morbidities.

No food or water is taken for one to two hour after medication.

Other unique side effects of bisphosphonates are -

*Osteonecrosis of jaw ( ONJ)
*Uveitis
*Atypical fractures ( especially in proximal femur)

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